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5240 Annunciation St, New Orleans, LA 70115, USA
- Mon11 AM – 3 PM
- Tue11 AM – 3 PM
- Wed · Today11 AM – 3 PM
- Thu11 AM – 5 PM
- Fri11 AM – 7 PM
- Sat11 AM – 7 PM
- SunClosed
How locals rank it
From the local food press
- Po-Boys
Large fried Gulf oysters fill Leidenheimer bread with lettuce, mayo, and ketchup at this Uptown sandwich counter.
Picks from NOLA.com | The Times-Picayune, Where Y'at, The Advocate | Gambit, and Eater New Orleans
- Sandwiches
Family-run since 1918, Domilise's is a New Orleans po-boy classic tucked into an unassuming Uptown neighborhood bar on Annunciation Street. The roast beef comes sloppy with gravy and the fried-shrimp and oyster po-boys are dressed to order, all built on Leidenheimer bread. A counter-and-cooler operation that has barely changed in a century.
Picks from NOLA.com | The Times-Picayune, Gambit (nola.com), and Garden & Gun
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